Personal sacrifice, personal loss: Who suffered most?

A friend, who is also a bit of a Harry Potter fan, sent me this captioned picture today and it got me thinking: of all the characters in the Rowling world who themselves survived the entire situation, which one would you say suffered most as a result of the Voldemort's rise to power and the war to defeat him?

The caption would suggest that Hermione made the greatest sacrifice and I might be willing consider this possibility (that Hermione made the greatest sacrifice of all by erasing herself from her parents’ memories) if it weren’t reversible.

But she can reverse it.

What cannot be reversed are the Weasley family’s losses (one son dead, two sons injured), nor the losses suffered by Mrs. Tonks (her husband [Ted Tonks], daughter [Nymphadora Tonks], son-in-law [Remus Lupin] and sister [Bellatrix Lestrange] were all killed, leaving her alone with a half-werewolf grandson). 

And you have to figure that Hermione and Ron set out for Australia fairly soon after the war ended with Voldemort’s death to track down her parents, reverse the obliviate spells she cast on them and remind them who she is!

Note, in Chapter five (the last chapter I’ve finished) of The Way Forward, my fan fiction post-Deathly Hallows novel, I make it clear that Hermione and Ron go to Australia to retrieve her parents!

I will have to take some more time to think about this question as I am sure there are a whole cast of characters, minor or major, who suffered great losses as a result of the events of the Rowling books.

The "club-house leader" is Mrs. Tonks, by the way. But is there someone out there who sacrificed more?